What genotype indicates a person has polycystic kidney disease?

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Multiple Choice

What genotype indicates a person has polycystic kidney disease?

Explanation:
Polycystic kidney disease in this context is autosomal dominant, so having just one copy of the disease-causing allele is enough to develop the condition. If we use P for the disease allele and p for the normal allele, any genotype that includes at least one P—PP or Pp—will express the disease. A genotype with two normal alleles, pp, would be unaffected. So the correct idea is that disease is present with PP or Pp, while pp would not show the disease.

Polycystic kidney disease in this context is autosomal dominant, so having just one copy of the disease-causing allele is enough to develop the condition. If we use P for the disease allele and p for the normal allele, any genotype that includes at least one P—PP or Pp—will express the disease. A genotype with two normal alleles, pp, would be unaffected. So the correct idea is that disease is present with PP or Pp, while pp would not show the disease.

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